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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

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Pediatric Scleritis: An Update.

Maria Tarsia1, Carla Gaggiano1,2, Elisa Gessaroli2

  • 1Clinical Pediatrics, Department of Molecular Medicine and Development, University of Siena, Siena, Italy.

Ocular Immunology and Inflammation
|February 28, 2022
PubMed
Summary

Posterior idiopathic scleritis is common in children, but other forms can signal systemic diseases. Prompt diagnosis and tailored treatment are crucial for preventing ocular and systemic complications.

Keywords:
Scleritisbiologicsdiagnosisimmunosuppressive agentsintraocular inflammationpediatric scleritistreatment

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Area of Science:

  • Ophthalmology
  • Pediatric Rheumatology

Background:

  • Posterior idiopathic scleritis is the most common scleritis type in children.
  • Anterior and necrotizing scleritis can also occur, sometimes linked to systemic disorders.

Purpose of the Study:

  • To highlight the importance of recognizing systemic associations in childhood scleritis.
  • To emphasize the need for prompt diagnosis and multidisciplinary work-up to prevent complications.

Main Methods:

  • Review of clinical presentations and diagnostic approaches for childhood scleritis.
  • Discussion of potential infectious and autoimmune etiologies.
  • Emphasis on multidisciplinary diagnostic strategies.

Main Results:

  • Childhood scleritis, while often posterior and idiopathic, can indicate underlying systemic conditions.
  • Prompt identification of infectious or autoimmune causes (e.g., ANCA-associated vasculitis, sarcoidosis) is vital.
  • Systemic associations require specific management to avoid severe outcomes.

Conclusions:

  • Childhood scleritis necessitates a thorough diagnostic evaluation to exclude systemic diseases.
  • Treatment must be individualized based on scleritis type, severity, and associated conditions.
  • Effective management preserves visual acuity and enhances quality of life.