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Cardio-Rheumatology: Prevention of Cardiovascular Disease in Inflammatory Disorders

Paul Nona1, Cori Russell1

  • 1Department of Internal Medicine, Division of Cardiology, 2799 West Grand Boulevard, Detroit, MI 48202, USA.

The Medical Clinics of North America
|March 1, 2022
PubMed

Insights

Chronic inflammation significantly increases cardiovascular disease risk, including coronary artery disease and heart failure. Current risk assessments underestimate this danger, leading to inadequate preventive care for affected individuals.

Area of Science:

  • Cardiovascular Medicine
  • Immunology
  • Public Health

Background:

  • Inflammation is a key driver in atherosclerosis development and progression.
  • Chronic inflammatory conditions elevate cardiovascular disease (CVD) risk, independent of traditional factors.
  • Existing cardiac risk assessment tools often underestimate risk in patients with chronic inflammation.

Purpose of the Study:

  • To highlight the underestimation of cardiac risk in individuals with chronic inflammation.
  • To underscore the lack of awareness regarding the inflammation-CVD link.
  • To address the resulting undertreatment in preventive cardiac care for this population.

Main Methods:

  • This study reviews existing literature on inflammation and cardiovascular disease.
  • It analyzes the limitations of traditional cardiovascular risk assessment tools.
  • It discusses the implications for preventive cardiology.

Main Results:

  • Chronic inflammation poses a significant, often underestimated, risk for cardiovascular diseases like coronary artery disease and heart failure.
  • Traditional risk calculators fail to adequately account for inflammation-related cardiac risk.
  • A significant gap exists in awareness and preventive strategies for patients with chronic inflammatory conditions.

Conclusions:

  • There is a critical need to integrate inflammatory markers into cardiovascular risk assessment.
  • Increased awareness and targeted preventive strategies are essential for patients with chronic inflammatory diseases.
  • Addressing the inflammation-cardiovascular disease link can improve preventive cardiac care and reduce morbidity.

Keywords:
Cardiovascular diseaseInflammationPreventionRheumatoid arthritisSystemic lupus erythematosus

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