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Evaporation-reducing Culture Condition Increases the Reproducibility of Multicellular Spheroid Formation in Microtiter Plates
Published on: March 7, 2017
Jonathan Vacher1, Claire Launay2, Ruben Coen-Cagli3
1Department of Systems & Computational Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, 10461, NY, USA; Laboratoire des Systèmes Perceptif, Département d'Études Cognitives, École Normale Supérieure, PSL University, 24 rue Lhomond, Bâtiment Jaurès, 2éme étage, Paris, 75005, France.
This study introduces a flexible Dirichlet distribution parametrization for regularizing mixture model mixing probabilities. The method enhances unsupervised clustering and image segmentation by adapting to data topology, improving model inference.
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