Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids01:21

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

231
Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
231
Glaucoma: Overview01:25

Glaucoma: Overview

938
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
938
Vision01:24

Vision

55.7K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
55.7K
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

4.6K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
4.6K
Vitamins01:30

Vitamins

1.0K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
1.0K
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents01:29

Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

282
Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
282

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retinal sublayer changes in cases with Alzheimer's disease and depression.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

The effects of netarsudil ophthalmic solution on the expression of genes involved in fibrogenesis in orbital fibroblasts of patients with thyroid eye disease.

Molecular biology reports·2026
Same author

<i>In Silico</i> Design and Analysis of a Novel Ranibizumab-derived Peptide against the Vascular Endothelial Growth Factor.

Journal of ophthalmic & vision research·2026
Same author

Advancing glaucoma treatment with nanotechnology: a new frontier in ophthalmology.

International journal of pharmaceutics·2025
Same author

Macular Sublayer Thickness in Healthy Iranian Children: An Optical Coherence Tomography Study from the Population-Based Shiraz Pediatric Eye Study.

Journal of current ophthalmology·2025
Same author

Concurrent inheritance of achromatopsia and MMAT syndrome in a pedigree: Genetic and clinical insights.

European journal of medical genetics·2025
Same journal

Compressed air ocular barotrauma from high pressure industrial ice-dispensing system failure: an unusual occupational hazard.

Clinical & experimental optometry·2026
Same journal

An international survey of low vision rehabilitation services.

Clinical & experimental optometry·2026
Same journal

Readiness of the tabletop screen-based perimetry tests for screening and monitoring glaucoma.

Clinical & experimental optometry·2026
Same journal

Validation of the vision quality of life-time survey: comparison with the convergence insufficiency symptom survey.

Clinical & experimental optometry·2026
Same journal

Measuring contrast sensitivity in school children and young adults: a comparison between Pelli-Robson and SpotChecks charts.

Clinical & experimental optometry·2026
Same journal

Three-year retinal and visual outcomes after ultraviolet- and blue light-filtering intraocular lenses.

Clinical & experimental optometry·2026
See all related articles

Related Experiment Video

Updated: Oct 1, 2025

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
07:08

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

10.2K

Crocin as a vision supplement.

Mojtaba Heydari1,2, Mousa Zare2, Mohammad Reza Badie2

  • 1Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Clinical & Experimental Optometry
|March 1, 2022
PubMed
Summary
This summary is machine-generated.

Crocin, a saffron compound, shows promise for vision health and treating eye diseases like glaucoma and macular degeneration. Further clinical studies are needed to confirm its benefits as a vision supplement.

Keywords:
Crocineyenaturalnutritionretinasaffronsupplement

More Related Videos

Using the Horseshoe Crab, Limulus Polyphemus, in Vision Research
14:28

Using the Horseshoe Crab, Limulus Polyphemus, in Vision Research

Published on: July 3, 2009

14.4K
In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy
06:19

In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy

Published on: November 11, 2017

10.8K

Related Experiment Videos

Last Updated: Oct 1, 2025

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
07:08

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

10.2K
Using the Horseshoe Crab, Limulus Polyphemus, in Vision Research
14:28

Using the Horseshoe Crab, Limulus Polyphemus, in Vision Research

Published on: July 3, 2009

14.4K
In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy
06:19

In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy

Published on: November 11, 2017

10.8K

Area of Science:

  • Ophthalmology and Pharmacology.
  • Natural product research.

Background:

  • Crocin, derived from saffron (Crocus sativus L.), is investigated for its therapeutic potential in various ophthalmic conditions.
  • Eye diseases such as glaucoma, macular dystrophies, diabetic retinopathy, and age-related macular degeneration are significant causes of vision impairment.

Approach:

  • This review synthesizes preclinical and clinical evidence on crocin's role in eye health.
  • It examines the pathophysiological mechanisms underlying crocin's effects on retinal tissues and ophthalmic diseases.

Key Points:

  • Preclinical studies demonstrate crocin's cytoprotective, antioxidative, anti-inflammatory, and hemorheologic properties in retinal tissue.
  • Crocin modulates retinal pathologies via PI3K/Akt activation and NF-κB inhibition.
  • Clinical evidence indicates crocin improves outcomes in patients with retinal degenerations, dystrophies, and glaucoma.

Conclusions:

  • Crocin exhibits potential as a vision supplement for both healthy individuals and patients with existing eye conditions.
  • Additional large-scale, long-term clinical trials are necessary to validate these findings and establish definitive therapeutic recommendations.