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Published on: February 3, 2021
[Personalized Therapeutic Concepts in Chronic Coronary Syndromes]
Julia Stehli1, Philipp Jakob1, Jonathan Michel1
1Klinik für Kardiologie, Universitäres Herzzentrum, Universitätsspital Zürich, Zürich.
Insights
Chronic coronary syndromes (CCS) involve significant health risks due to coronary artery changes. This review details current CCS management, emphasizing invasive assessment and treatment strategies for better patient outcomes.
Area of Science:
- Cardiology
- Internal Medicine
- Vascular Biology
Background:
- Chronic coronary syndromes (CCS) contribute significantly to patient morbidity and mortality.
- Myocardial ischemia in CCS stems from obstructive or non-obstructive coronary artery alterations.
- These alterations involve both epicardial vessels and the coronary microvasculature.
Purpose of the Study:
- To review the contemporary management of patients diagnosed with chronic coronary syndromes.
- To highlight the importance of invasive assessment in diagnosing and managing CCS.
- To discuss the role of interventional treatments in CCS.
Main Methods:
- Review of current diagnostic algorithms for suspected CCS.
- Analysis of therapeutic strategies including lifestyle changes and medical therapy.
- Focus on invasive imaging and functional testing for CCS evaluation.
Main Results:
- Diagnostic pathways for CCS integrate various non-invasive and invasive techniques.
- Optimal medical therapy is a cornerstone of CCS management.
- Coronary revascularization is indicated in specific patient subgroups.
Conclusions:
- Personalized therapeutic concepts are crucial for managing CCS effectively.
- Invasive assessment plays a pivotal role in guiding treatment decisions for CCS.
- A comprehensive approach combining medical and interventional strategies optimizes CCS care.
Abstract:
Personalized Therapeutic Concepts in Chronic Coronary Syndromes Abstract. Chronic coronary syndromes (CCS) are related to substantial morbidity and mortality. Myocardial ischemia in CCS is caused by either obstructive or non-obstructive alterations of the coronary arteries, including both morphological and functional changes of epicardial vessels and the coronary microvasculature. Diagnostic algorithms of patients with suspected CCS include non-invasive and invasive imaging and functional testing. Therapeutic management comprises lifestyle changes, optimal medical therapy, and coronary revascularization when indicated. This review summarizes the contemporary management of patients with CCS, focusing on the role of invasive assessment and treatment.
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