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Abstract:
Advances in surgical techniques have made vitreoretinal and sclerochorio-retinal biopsies part of the available diagnostic armamentarium of the ophthalmologist. Special studies can be performed on tissue obtained in this way in order to provide a specific etiologic diagnosis of virus associated pathology. The advantages and disadvantages of immunopathologic and ultrastructural methods, tissue culture, and nucleic acid hybridization techniques for viral identification are compared and discussed.