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Fluorescein angiography complication survey.

L A Yannuzzi, K T Rohrer, L J Tindel

    Ophthalmology
    |May 1, 1986
    PubMed
    Summary
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    Intravenous fluorescein angiography has low rates of severe complications, with moderate reactions occurring in 1:63 cases and severe reactions in 1:1900. This national survey provides crucial safety data for ophthalmic procedures.

    Area of Science:

    • Ophthalmology
    • Medical Imaging
    • Public Health

    Background:

    • Intravenous fluorescein angiography is a common diagnostic tool in ophthalmology.
    • Understanding the frequency and nature of adverse reactions is crucial for patient safety.
    • Previous studies on fluorescein angiography complications have varied in scope and methodology.

    Purpose of the Study:

    • To determine the incidence of moderate and severe complications associated with intravenous fluorescein angiography.
    • To analyze the characteristics and outcomes of adverse reactions.
    • To provide updated safety data for ophthalmic practitioners.

    Main Methods:

    • A national survey of ophthalmologists was conducted.
    • Data collected on 221,781 fluorescein angiograms performed in 1984.

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  • Adverse reactions were categorized as mild, moderate, severe, or death based on specific criteria.

    • Main Results:

    • The frequency of moderate reactions was 1:63.
    • The frequency of severe reactions was 1:1900.
    • The frequency of death was 1:222,000.

    Conclusions:

    • Intravenous fluorescein angiography demonstrates a low rate of severe complications.
    • The study provides valuable epidemiological data on the safety profile of fluorescein angiography.
    • Recommendations for complication prevention and management are discussed.