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Obesity Does Not Increase Risk for Mortality in Severe Sepsis Trauma Patients

E Tay-Lasso1, A Grigorian1, M Lekawa1

  • 1Department of Surgery, University of California, Irvine, Division of Trauma, Burns and Surgical Critical Care, Orange, CA, USA.

The American Surgeon
|March 3, 2022
PubMed

Insights

Obese trauma patients with severe sepsis experienced longer hospital stays but had a similar mortality risk compared to normal BMI patients. This finding suggests obesity does not increase mortality in this critical patient group.

Area of Science:

  • Trauma and Critical Care Medicine
  • Sepsis Pathophysiology
  • Obesity Epidemiology

Background:

  • Obesity affects up to 40% of US adults.
  • Obese patients with severe sepsis show lower mortality than normal BMI patients.
  • This study investigates obesity's impact on mortality in severe sepsis trauma patients.

Purpose of the Study:

  • To test the hypothesis that obese trauma patients with severe sepsis have decreased mortality risk.
  • To compare mortality risk between obese and normal BMI trauma patients with severe sepsis.

Main Methods:

  • Utilized the 2017 Trauma Quality Improvement Program database.
  • Included adult trauma patients with severe sepsis and documented BMI.
  • Grouped patients into non-obese (BMI <30 kg/m²) and obese (BMI ≥30 kg/m²).
  • Employed multivariable logistic regression for mortality analysis.

Main Results:

  • Analyzed 1246 patients: 566 non-obese (42.4%) and 680 obese (57.6%).
  • Obese trauma patients (OTP) had longer length of stay (LOS), ICU LOS, and ventilator days (P < .001).
  • After covariate adjustment, overweight, obese, severely obese, and morbidly obese patients showed similar mortality risk compared to normal BMI patients.

Conclusions:

  • Obese trauma patients with severe sepsis experienced increased LOS, ICU LOS, and ventilator days.
  • Increasing degrees of obesity were associated with similar mortality risk compared to normal BMI trauma patients with severe sepsis.
Abstract

Keywords:
mortalityobesitysevere sepsis

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