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Updated: Oct 1, 2025

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
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Simulated nonlinear genetic and environmental dynamics of complex traits

Michael D Hunter1, Kevin L McKee2, Eric Turkheimer3

  • 1Department of Human Development and Family Studies, The Pennsylvania State University, University Park, PA, USA.

Development and Psychopathology
|March 3, 2022
PubMed
Summary

This study simulates complex trait development, revealing that genome-wide association studies miss gene-environment interactions. Including related individuals in genome-wide complex trait analysis (GCTA) recovers these interactions, explaining the "missing heritability" in genetic studies.

Keywords:
GWASbehavior geneticsdynamical systemsheritabilitysimulation

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