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Updated: Oct 1, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Clinical profile of dengue in the elderly using surveillance data from two epidemics
Yara Hahr Marques Hökerberg1,2,3, Fernanda Kohn1,2, Taís Suane de Souza3
1Fundação Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Laboratório de Epidemiologia Clínica, Rio de Janeiro, RJ, Brasil.
Background:
Population aging and mobility have increased the exposure of elderly individuals to dengue. This study evaluated the clinical features of dengue in the elderly during the epidemic (2008 and 2012) and interepidemic (2009 and 2010) periods.
Methods:
This cross-sectional study was based on dengue surveillance data from Rio de Janeiro, Brazil: 2008 (n=31,210), 2009‒2010 (n=2,884), and 2012 (n=30,773). The analysis was stratified by age group (<60 and ≥60 years).
Results:
Case-fatality rates were higher in the elderly. In 2008, elderly individuals were found to be more prone to hematuria and thrombocytopenia.
Conclusions:
These results can improve the understanding of dengue in elderly individuals who live in or travel to tropical regions.
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