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[Research progress on the relationship between epigenetics and neuroblastoma in children]

S D He1, X L Ma1

  • 1Medical Oncology Department, Pediatric Oncology Center,Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing Key Laboratory of Pediatric Hematology Ocology, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing 100045, China.

Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics
|March 3, 2022
PubMed
Abstract

No abstract available in PubMed .

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Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
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