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Delayed multiple intracranial aneurysms caused by left atrial myxoma: a case report and literature review

Aihua Wang1, Zhaoxia Wang2, Ke Hu3

  • 1Department of Neurology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Institute of Neuroimmunology, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, Jinan, China.

Translational Pediatrics
|March 4, 2022
PubMed

Insights

Cardiac myxoma removal may prevent initial neurological symptoms but not delayed intracranial aneurysms. A neoplastic process may cause these delayed aneurysms, requiring comprehensive treatment.

Area of Science:

  • Cardiology
  • Neurology
  • Oncology

Background:

  • Left atrial myxoma can cause neurological deficits.
  • The development of intracranial aneurysms after myxoma resection is not well understood.

Observation:

  • A 14-year-old male presented with stroke-like symptoms due to a left atrial myxoma.
  • Despite successful surgical removal, multiple intracranial aneurysms developed 18 months later.
  • The patient remained neurologically stable for 5 years with conservative management.

Findings:

  • Atrial myxoma resection can resolve acute neurological symptoms.
  • Delayed intracranial aneurysms can occur post-myxoma resection.
  • The neoplastic process is a potential cause of these delayed aneurysms.

Implications:

  • Early neurological symptoms from myxoma do not preclude delayed aneurysm formation.
  • A multimodal treatment approach including surgery, chemotherapy, radiotherapy, and embolization may be necessary for delayed aneurysms.
  • Further research into the pathogenesis of delayed intracranial aneurysms post-myxoma is warranted.

Keywords:
Multiple intracranial aneurysmscase reportcomputed tomography angiography (CTA)left atrial myxomamagnetic resonance imaging (MRI)

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