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Published on: June 18, 2013
Fabrication of a hierarchical nanoreactor based on COFs for cascade enzyme catalysis
Xiaolian Yang1, Zheng Tan1, Hanjun Sun2
1Key Laboratory of Drug Quality Control and Pharmacovigilance Ministry of Education, China Pharmaceutical University, Nanjing 211198, China.
Abstract:
A hierarchical nanoreactor based on covalent organic frameworks (COFs) was fabricated using polystyrene spheres (PSs) as a template. When applied in cascade catalysis, the nanoreactor significantly improved the catalytic activity of internal enzymes, and showed protection for the enzyme in harsh environments. Moreover, glucose can be sensitively detected (detection sensitivity: 10 μM) by the nanoreactor.
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