Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toward autonomous robotic-assisted and microrobotic surgery.

Science advances·2026
Same author

A Safe Framework for Quantitative In Vivo Human Evaluation of Image Guidance.

IEEE open journal of engineering in medicine and biology·2024
Same author

Autonomous medical needle steering in vivo.

Science robotics·2023
Same author

Deep Learning Segmentation of the Nucleus Basalis of Meynert on 3T MRI.

AJNR. American journal of neuroradiology·2023
Same author

Social brain networks: Resting-state and task-based connectivity in youth with and without epilepsy.

Neuropsychologia·2021
Same author

A multi-subject accuracy study on granular jamming for non-invasive attachment of fiducial markers to patients.

International journal of computer assisted radiology and surgery·2019

Related Experiment Video

Updated: Oct 1, 2025

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

12.6K

Targeting Epilepsy Through the Foremen Ovale: How Many Helical Needles are Needed?

J Granna1,2, E B Pitt1,2, M E McKay1,2

  • 1Mechanical Engineering Department, Vanderbilt University, Nashville, TN, USA.

Annals of Biomedical Engineering
|March 4, 2022
PubMed
Summary
This summary is machine-generated.

A new study suggests three standard helical needle shapes can precisely target the hippocampus for epilepsy treatment, reducing the need for patient-specific designs. This approach minimizes brain tissue damage during laser ablation therapy.

Keywords:
Concentric tube robotsMinimally-invasive surgeryOptimizationRobotic surgerySteerable needles

More Related Videos

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring
11:28

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Published on: June 13, 2025

645
Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

17.4K

Related Experiment Videos

Last Updated: Oct 1, 2025

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

12.6K
Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring
11:28

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Published on: June 13, 2025

645
Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

17.4K

Area of Science:

  • Neurosurgery
  • Medical Device Engineering
  • Epilepsy Treatment

Background:

  • Laser ablation of the hippocampus is an alternative to surgery for refractory epilepsy.
  • Current methods use burr holes, causing significant brain tissue disruption.
  • A novel approach uses a helical needle via the foramen ovale for more precise hippocampal targeting.

Purpose of the Study:

  • To determine if patient-specific helical needles are necessary or if a limited set of pre-defined shapes suffices.
  • To develop an optimization strategy for selecting a universal needle set.
  • To evaluate the accuracy of pre-defined helical needles in reaching the hippocampal medial axis.

Main Methods:

  • Proposed a new optimization strategy using patient data to define a universal needle set.
  • Investigated the accuracy of helical needles in reaching the hippocampal medial axis.
  • Utilized 20 patient datasets from 10 CT scans to analyze needle trajectory accuracy.

Main Results:

  • A small set of three basic helical tube shapes (with mirroring for left/right hippocampi) is sufficient.
  • This approach reduces the worst-case maximum error to below 2 mm.
  • The findings support the use of standardized helical needle designs.

Conclusions:

  • Standardized helical needles can effectively and accurately target the hippocampus for laser ablation therapy.
  • This reduces the complexity and cost associated with patient-specific device fabrication.
  • The foramen ovale access path with helical needles offers a minimally invasive and precise epilepsy treatment option.