Prognostic value of atrial strain in non-ischemic dilated cardiomyopathy

La Tunisie Medicale
|March 4, 2022
PubMed

Insights

Left atrial function assessed by 2D speckle tracking echocardiography can identify patients with dilated cardiomyopathy at high cardiovascular risk. Lower atrial peak-systolic longitudinal strain and time to peak atrial longitudinal strain indicate increased risk of adverse events.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiovascular Imaging

Background:

  • Left atrial function is often underestimated in non-ischemic dilated cardiomyopathy (DCM).
  • Several ultrasound parameters of left atrial function are emerging as potential risk markers for DCM patients.

Purpose of the Study:

  • To evaluate left atrial function using 2D speckle tracking echocardiography (STE).
  • To determine the prognostic value of left atrial function parameters in dilated cardiomyopathy.

Main Methods:

  • Prospective study of 40 DCM patients over 6 months.
  • Echocardiography with 2D speckle tracking performed at baseline.
  • Primary endpoint: occurrence of major cardiovascular events.

Main Results:

  • 25 patients experienced major cardiovascular events, including ventricular arrhythmias and heart failure decompensation.
  • No significant differences in cardiovascular risk factors, symptoms, or blood tests between groups.
  • Significantly lower atrial peak-systolic longitudinal strain (PALS) and time to peak atrial longitudinal strain (TPALS) in patients with events.

Conclusions:

  • 2D speckle tracking analysis of the left atrium aids in identifying high-risk DCM patients.
  • Improved risk stratification can lead to better patient management and follow-up.
Abstract

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