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Updated: Oct 1, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
Prognostic value of atrial strain in non-ischemic dilated cardiomyopathy
Insights
Left atrial function assessed by 2D speckle tracking echocardiography can identify patients with dilated cardiomyopathy at high cardiovascular risk. Lower atrial peak-systolic longitudinal strain and time to peak atrial longitudinal strain indicate increased risk of adverse events.
Area of Science:
- Cardiology
- Echocardiography
- Cardiovascular Imaging
Background:
- Left atrial function is often underestimated in non-ischemic dilated cardiomyopathy (DCM).
- Several ultrasound parameters of left atrial function are emerging as potential risk markers for DCM patients.
Purpose of the Study:
- To evaluate left atrial function using 2D speckle tracking echocardiography (STE).
- To determine the prognostic value of left atrial function parameters in dilated cardiomyopathy.
Main Methods:
- Prospective study of 40 DCM patients over 6 months.
- Echocardiography with 2D speckle tracking performed at baseline.
- Primary endpoint: occurrence of major cardiovascular events.
Main Results:
- 25 patients experienced major cardiovascular events, including ventricular arrhythmias and heart failure decompensation.
- No significant differences in cardiovascular risk factors, symptoms, or blood tests between groups.
- Significantly lower atrial peak-systolic longitudinal strain (PALS) and time to peak atrial longitudinal strain (TPALS) in patients with events.
Conclusions:
- 2D speckle tracking analysis of the left atrium aids in identifying high-risk DCM patients.
- Improved risk stratification can lead to better patient management and follow-up.
Introduction:
Left atrial function in non-ischemic dilated cardiomyopathy (DCM) has long been underestimated when studying the ultrasound parameters of DCM. Currently, several ultrasound parameters of left atrial function have been proposed as markers to detect patients at risk.
Aim:
To evaluate the left atriumfunctionwith 2D speckle tracking echocardiography and itsprognostic value in the dilatedcardiomyopathy.
Methods:
The study prospectively recruited 40 patients with dilated cardiomyopathy, between January and June 2014, followed up at the cardiology department of Habib Thameur Hospital of Tunis. An echocardiogram was performed for all patients at the beginning of the study. After a 6-month follow-up, the primary endpoint was the occurrence of a major cardiovascular event. The patients were divided into a first group without cardiovascular events (group 1) and a second group with a cardiovascular event (group 2).
Results:
During the follow-up, 25 patients presented a major cardiovascular event (8 ventricular arrhythmias and 17 hospitalizations for acute decompensated heart failure). There were no significant differences between the two groups regarding cardiovascular risk factors, symptoms and blood testing values.In addition, regarding results obtained from speckle tracking echocardiography, atrial peak-systolic longitudinal strain (PALS) and time to peak atrial longitudinal strain (TPALS) values were observed to be significantly lower in group 2 ( 34.6% in group 1 vs 28.4% in group 2, p=0.000; and 344.6ms in group 1 vs 349.8 ms in group 2, p=0.016 respectively).
Conclusion:
The analysis of the LA speckle tracking in the dilatedcardiomyopathymay help cardiologistto identify patients at high cardiovascular risk and thus improve their management and follow-up.
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