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Spurious results for total and free prostate-specific antigen (PSA); sometimes really "a riddle wrapped in a mystery

Romolo Marco Dorizzi1, Paolo Maltoni1, Claudio Sgarzani1

  • 1Clinical Pathology Unit, Hub Laboratory, AUSL Romagna, Cesena, Italy.

Clinical Chemistry and Laboratory Medicine
|March 5, 2022
PubMed
Abstract

No abstract available in PubMed .

Keywords:
free prostate-specific antigenimmuno-assaysinterferencestotal prostate-specific antigen

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In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
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