Related Experiment Video

Updated: Oct 1, 2025

Implantation of the Syncardia Total Artificial Heart
16:11

Implantation of the Syncardia Total Artificial Heart

Published on: July 18, 2014

35.5K

[Heart Transplantation for Older Patients]

Yoshihisa Tanoue1, Akira Shiose

  • 1Department of Advanced Cardiopulmonary Failure, Kyushu University Graduate School of Medicine, Fukuoka, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|March 6, 2022
PubMed

Insights

Japan

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Geriatric Medicine

Background:

  • Increasing number of older organ donors in Japan.
  • Aging recipient population due to longer waiting times for heart transplantation.
  • Age over 60 is a critical criterion for heart transplantation in Japan.

Purpose of the Study:

  • To evaluate the outcomes of heart transplantation using older donors and recipients.
  • To highlight the increasing trend of marginal cases in heart transplantation.
  • To emphasize the importance of careful donor and recipient evaluation.

Main Methods:

  • Retrospective analysis of 42 heart transplantations at an institution.
  • Categorization of cases based on donor and recipient age (over 60).
  • Review of patient discharge status.

Main Results:

  • 12 cases involved donors over 60 years old.
  • 7 cases involved recipients over 60 years old.
  • 4 cases had both donor and recipient over 60; all patients were discharged home.

Conclusions:

  • Heart transplantation with older donors and recipients is feasible and can achieve positive outcomes.
  • The increasing prevalence of older donors and recipients necessitates careful evaluation of marginal cases.
  • Thorough assessment of coronary lesions and comorbidities is crucial for successful transplantation decisions.

More Related Videos

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft08:30

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft

Published on: February 14, 2022

2.8K
Implantation of Total Artificial Heart in Congenital Heart Disease07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

24.8K

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
69
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
55
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
47
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
47
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
78