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Updated: Oct 1, 2025

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Published on: January 7, 2019
Targeting coagulation to unlock antitumor immunity?
Antoine Galmiche1,2, Zuzana Saidak1,2, François Ghiringhelli3
1EA7516 Chimere, Université de Picardie Jules Verne, Amiens, France.
Abstract:
Besides a number of physical consequences (reduced blood supply, stabilization of circulating tumor microemboli, shielding from the attack of immune cells), the coagulation cascade may specifically regulate antitumor immunity. We recently applied systems biology and genomics to explore the regulation of the tumor immune microenvironment by coagulation.
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