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Related Concept Videos

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Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
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DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
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Related Experiment Video

Updated: Oct 1, 2025

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
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Guidelines for de novo phasing using multiple small-wedge data collection. Corrigendum.

Seiki Baba1, Hiroaki Matsuura2, Takashi Kawamura1

  • 1Protein Crystal Analysis Division, Japan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo, Hyogo 679-5198, Japan.

Journal of Synchrotron Radiation
|March 7, 2022
PubMed
Summary

A correction is issued for a figure in a 2021 journal article by Baba et al. This ensures the accuracy of scientific data presented in the publication.

Keywords:
de novo phasingdoseprotein crystallographyradiation damagesmall-wedge synchrotron crystallography (SWSX)

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Area of Science:

  • Crystallography
  • Materials Science
  • Synchrotron Radiation

Context:

  • A previous publication by Baba et al. (2021) in the Journal of Synchrotron Radiation presented specific data.
  • Accurate representation of experimental results is crucial in scientific publications.

Purpose:

  • To correct an error in a figure within the specified article.
  • To maintain the integrity and reliability of published scientific findings.

Summary:

  • A specific figure in the article 'J. Synchrotron Rad. 28, 1284-1295' has been identified with an inaccuracy.
  • The authors have issued a correction to this figure to rectify the error.

Impact:

  • Ensures that researchers utilizing the data from Baba et al. (2021) have access to the corrected information.
  • Upholds scientific rigor by promptly addressing and correcting errors in published literature.