Related Experiment Video
Updated: Oct 1, 2025

Author Spotlight: Advancing Research in Corneal Opacity Treatment and Regeneration
Published on: August 4, 2023
Corneal Injury Risk Reduction During Sedation for Colonoscopy: An Evidence Based Practice Change
Aaron R Douthit1, Laurel Miner1, Nicholas G Bircher1
1Department of Nurse Anesthesia, University of Pittsburgh, Pittsburgh, PA.
Purpose:
This evidence-based practice change project examined the use of supine positioning as a substitute for lateral positioning after sedation for endoscopic procedures for the purpose of preventing corneal injuries in this patient population.
Design:
This study used a pre and post implementation design.
Methods:
Retrospective data was collected over 12 months, including 4,422 endoscopic procedures for comparison to the prospective data collected after implementing the practice change, which totaled eight months and 3080 procedures.
Findings:
Incidence rates for corneal injury and eye irritation were 0.158% before the practice change, with a decrease in incidence to 0.097% after the change. Using a two-sided Fisher's exact test, the results were not statistically significant (P => .05). Additionally, linear regression showed a slight downward trend with implementation; however, these results were also not statistically significant.
Conclusions:
The intervention did not have a statistically significant impact on the incidence of corneal injury. It is possible that more than one risk factor was contributing to corneal injury in this setting and the intervention only addressed one potential risk factor.
Related Concept Videos
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures II: Colonoscopy

