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Valve-in-Valve Using Perceval Prostheses for Prosthetic Valve Endocarditis.
Quynh Nguyen1, Abigail White2, Wing Lam3
1Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Surgical treatment for prosthetic valve endocarditis is challenging. Redo aortic valve replacement using the Perceval prosthesis via a valve-in-valve technique showed excellent hemodynamic performance in 3 patients.
Area of Science:
- Cardiovascular Surgery
- Prosthetic Valve Endocarditis Research
- Medical Device Innovation
Background:
- Prosthetic valve endocarditis (PVE) poses significant surgical challenges.
- Rapid deployment valves offer potential solutions for redo surgery and complex aortic root anatomy.
- The valve-in-valve technique is an emerging approach for PVE management.
Observation:
- This report details 3 cases of PVE requiring redo aortic valve replacement.
- The Perceval (LivaNova) prosthesis was utilized in a valve-in-valve approach for these patients.
- Patient selection considered infective endocarditis in a redo setting and challenging aortic root conditions.
Findings:
- All 3 patients successfully underwent redo aortic valve replacement with the Perceval prosthesis.
- The valve-in-valve technique was feasible and applied in these complex PVE cases.
- Excellent hemodynamic performance of the Perceval prostheses was observed perioperatively and during follow-up.
Implications:
- The Perceval prosthesis via valve-in-valve may be a viable option for select PVE patients.
- This technique could offer improved outcomes in challenging redo aortic valve surgery for endocarditis.
- Further research is warranted to establish the long-term efficacy and safety of this approach.
Related Concept Videos
Mitral Stenosis III: Medical Management
Endocarditis III: Medical Management
Endocarditis I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Endocarditis IV: Nursing Management
Mitral Valve Prolapse I: Introduction

