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Autoimmune Disorders

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...

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Related Experiment Video

Updated: Oct 1, 2025

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

Published on: July 4, 2007

[Autoimmune encephalitis : an update].

Adonis Mattar¹, Jérôme Honnorat², Bastien Joubert³

¹Centre français de référence des syndromes neurologiques paranéoplasiques et des encéphalites auto-immunes, Hospices civils de Lyon ; Hôpital neurologique de Bron ; Hôpital neurologique de Lyon, France.

La Revue Du Praticien

|March 8, 2022

Summary

This summary is machine-generated.

Autoimmune encephalitis (AE) involves the central nervous system and is linked to anti-neuron antibodies. Treatment focuses on cancer and immune suppression for better patient outcomes.

Keywords:

Autoimmune Diseases

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Last Updated: Oct 1, 2025

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

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Published on: July 4, 2007

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

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Published on: September 9, 2022

Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo

Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo

Published on: March 26, 2019

Area of Science:

Neurology
Immunology
Neuroscience

Background:

Autoimmune encephalitis (AE) are rare central nervous system autoimmune disorders.
They are characterized by the presence of anti-neuron antibodies.
Clinical presentation varies based on the specific autoantibody involved.

Purpose of the Study:

To provide an update on the understanding and management of autoimmune encephalitis.
To differentiate between AE subtypes based on antibody targets and prognosis.
To highlight diagnostic and therapeutic strategies for AE.

Main Methods:

Review of current literature on autoimmune encephalitis.
Analysis of clinical presentations associated with different autoantibodies.
Discussion of diagnostic approaches, including antibody detection.
Overview of management strategies, including immunotherapy and cancer treatment.

Main Results:

AE with intracellular antibodies often indicate paraneoplastic syndromes with poor prognosis.
AE with cell-surface antibodies are less frequently associated with cancer and generally have better outcomes.
Diagnosis is confirmed by detecting specific anti-neuron antibodies.

Conclusions:

Autoimmune encephalitis requires accurate diagnosis through antibody detection.
Management involves addressing underlying neoplasia and employing immunosuppressive therapies.
Distinguishing AE subtypes based on antibody targets is crucial for predicting prognosis and guiding treatment.