Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

68
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
68
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

82
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
82
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

90
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
90
Tissue Transplantation01:24

Tissue Transplantation

546
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
546

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Single Versus Dual Kidney Transplants From Marginal Donors: Balancing Survival and Resource Utilization.

Journal of transplantation·2025
Same author

<i>Ex vivo</i> investigation of the effect of the transverse arytenoid ligament on abduction of the arytenoid cartilage when performing equine laryngoplasty.

New Zealand veterinary journal·2019
Same author

Preformed Angiotensin II Type-1 Receptor Antibodies Are Associated With Rejection After Kidney Transplantation: A Single-Center, Cohort Study.

Transplantation proceedings·2018
Same author

A data-driven patient blood management strategy in liver transplantation.

Vox sanguinis·2018
Same author

Are we underestimating the quality of aviremic hepatitis C-positive kidneys? Time to reconsider.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2018
Same author

Unintended Consequences in Use of Increased Risk Donor Kidneys in the New Kidney Allocation Era.

Transplantation proceedings·2018

Related Experiment Video

Updated: Oct 1, 2025

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
08:39

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

Published on: November 7, 2020

8.0K

Optimizing Risk Assessment In Simultaneous Liver and Kidney Transplant: Donor and Recipient Factors Associated With

J B Hendele1, J D Perkins1, N Leca2

  • 1Division of Transplant Surgery, Department of Surgery.

Transplantation Proceedings
|March 9, 2022
PubMed
Summary
This summary is machine-generated.

Simultaneous liver and kidney (SLK) transplant outcomes are influenced by patient and donor factors. Identifying these characteristics can help clinicians optimize patient selection for SLK and liver transplant alone (LTA) procedures.

More Related Videos

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.5K
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

2.6K

Related Experiment Videos

Last Updated: Oct 1, 2025

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
08:39

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

Published on: November 7, 2020

8.0K
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.5K
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

2.6K

Area of Science:

  • Transplantation Medicine
  • Nephrology
  • Hepatology

Background:

  • Liver transplant alone (LTA) with a safety net for subsequent kidney transplant was introduced to aid decision-making in unclear renal recovery cases.
  • Simultaneous liver and kidney (SLK) transplantation is a complex procedure requiring careful patient selection.

Purpose of the Study:

  • To identify recipient and donor characteristics associated with poor post-transplant outcomes in SLK recipients.
  • To inform clinical decision-making regarding LTA versus SLK for patients with liver failure and uncertain renal prognosis.

Main Methods:

  • Analysis of the United Network for Organ Sharing database for SLK recipients from January 1, 2015.
  • Univariate analysis of recipient and donor factors against 1-year patient and graft survival.
  • Multivariable Cox regression analysis controlling for donor risk index variables.

Main Results:

  • Older recipients with higher Model for End-Stage Liver Disease scores, diabetes, recent dialysis, and ICU admission at transplant had lower 1-year survival.
  • Older donors and those with a higher Kidney Donor Profile Index were associated with poorer patient survival post-SLK.
  • Specific donor and recipient factors predict adverse outcomes after SLK.

Conclusions:

  • Recipient age, liver disease severity, comorbidities, and donor age are critical factors influencing SLK success.
  • These findings can guide clinicians in selecting appropriate candidates for SLK versus LTA, improving resource allocation and patient outcomes.