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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

321
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
321
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

297
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
297
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

304
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
304
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

858
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
858

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Articles linked to this work by shared authors, journal, and citation graph.

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The Evolving Kidney Donor Pool Shaping Outcomes in Graft Survival.

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Tailoring Kidney Transplant Strategies: Unraveling the Impact of Acute Kidney Injury and Preservation Methods Across Different Strata of Kidney Risk.

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Simultaneous Liver and Kidney Transplantation in Patients Aged 70 y and Older: Proceed With Caution.

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Kidney retransplantation outcomes in adults aged 70 and older: Analysis of risk factors and survival.

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Optimizing Risk Assessment In Simultaneous Liver and Kidney Transplant: Donor and Recipient Factors Associated With Improved Outcome.

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Related Experiment Video

Updated: Jan 12, 2026

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
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Single Versus Dual Kidney Transplants From Marginal Donors: Balancing Survival and Resource Utilization.

Kaufman D M1, J D Perkins1,2, Bakthavatsalam R1

  • 1Division of Transplant Surgery, Department of Surgery, University of Washington, Seattle, Washington, USA.

Journal of Transplantation
|November 3, 2025
PubMed
Summary

Dual kidney transplants show improved graft survival compared to single transplants. This approach could increase successful transplants and reduce waitlist deaths, optimizing donor kidney utilization for aging populations with kidney disease.

Keywords:
dual kidney transplantkidney graft survivalkidney transplant patient survivalsingle kidney transplant

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Area of Science:

  • Nephrology
  • Transplantation
  • Geriatrics

Background:

  • Aging populations and rising kidney disease prevalence increase demand for kidney transplants.
  • Organ shortage necessitates expanding donor pools, including dual kidney transplants from a single donor.
  • Current criteria for single vs. dual kidney transplantation suitability are inconsistent.

Purpose of the Study:

  • To compare patient and graft survival rates and graft function between single and dual kidney transplantation.
  • To analyze survival differences between single and dual kidney transplantation strategies.

Main Methods:

  • Retrospective analysis of the Organ Procurement and Transplantation Network database (2014-2024).
  • Inclusion of deceased donor kidney transplants, excluding en bloc donors.
  • Utilized 3:1 propensity matching for comparative analysis.

Main Results:

  • Dual kidney transplant donors were older with higher Kidney Donor Risk Index (KDRI) and increased glomerulosclerosis.
  • No significant difference in overall patient survival was observed between single and dual transplants.
  • Dual kidney transplantation demonstrated significantly increased graft survival.

Conclusions:

  • Optimizing outcomes requires careful donor and recipient matching in kidney transplantation.
  • Maximizing survival benefit from each donor kidney is essential, suggesting a role for dual transplants.