[Botryomycosis].

Area of Science:

• Dermatology
• Infectious Diseases
• Microbiology

Context:

• Botryomycosis is a rare bacterial granuloma.
• Fistulous and ulcerated lesions of the lower limbs are characteristic presentations.
• Associated osteomyelitis is common in botryomycosis cases.

Purpose:

• To present four cases of botryomycosis.
• To highlight diagnostic methods for botryomycosis.
• To report treatment outcomes for botryomycosis.

Summary:

• Four patients with botryomycosis affecting the lower limbs are described.
• Diagnosis involved clinical examination, direct microscopy for characteristic 'grains', and bacterial culture.
• All patients presented with concurrent osteomyelitis.

Impact:

• Successful treatment of botryomycosis was achieved in three patients using antibiotics or sulfonamides.
• Treatment efficacy was guided by antimicrobial susceptibility testing.
• This case series underscores the importance of timely diagnosis and appropriate antimicrobial therapy for botryomycosis.