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Progress of proteomics-driven precision medicine: From a glycosylation view

Yuying Liang1, Bin Fu1, Ying Zhang1,2

  • 1Shanghai Cancer Center and Department of Chemistry, Fudan University, Shanghai, People's Republic of China.

Rapid Communications in Mass Spectrometry : RCM
|March 9, 2022
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Glycans, a class of complex heterogeneous molecules, can be covalently attached to proteins to form glycosylated proteins that regulate various physiological and pathological processes. Glycosylated proteins or glycoproteins comprise N-linked and O-linked oligosaccharides. O-glycosylation is the most common type of protein glycosylation. Here, glycans attach to the oxygen atom of the hydroxyl groups of Serine or Threonine residues. O-linked glycosylation occurs later in protein processing,...
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