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Efficacy of Core Needle Biopsy in the Diagnosis of Pediatric Extracranial Solid Malignancies: A 10-Year Study
Arun Kumar Loganathan1, Tarun John Jacob1, Leni Grane Matthew2
1Department of Paediatric Surgery, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Introduction:
Core needle biopsies of solid masses in children are a minimally invasive technique. It guides to a definitive diagnosis and facilitates management.
Aims And Objectives:
To determine the accuracy, sensitivity, and specificity of core needle biopsies in diagnosing pediatric solid masses.
Materials And Methods:
A retrospective analysis of 430 children, who underwent core needle biopsy for solid masses between January 2007 and December 2016 at CMC Vellore, was done.
Results:
Retroperitoneal and intra-abdominal masses constituted 66% of cases. Real-time image guidance was used in 44% of cases. An accurate diagnosis was obtained in 93.6% of cases, while results did not correlate with the final diagnosis in 3.4%. Three percent had inadequate or necrotic tissue. None of the children had postprocedure complications.
Conclusion:
Core needle biopsies serve as good diagnostic modality, with minimal risks, in making a conclusive diagnosis and deciding on the line of management.
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