Regioselective fabrication of gold nanowires using open-space laminar flow for attomolar protein detection
Yuki Nishitani1, Nahoko Kasai2, Hizuru Nakajima1
1Yuki Nishitani, Hizuru Nakajima, Shungo Kato, Sifeng Mao, Katsumi Uchiyama, Department of Applied Chemistry, Graduate School of Urban Environmental Sciences, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji-Shi, Tokyo 192-0397, Japan. maosifeng@tmu.ac.jp.
Abstract:
Gold nanowires are expected to be applied to biosensing due to their advantages, such as high stability and biocompatibility. However, it is still inconvenient to fabricate a single gold nanowire at a precise position, and without a special demanding environment. In this study, we present an open-space laminar flow approach for fabricating a single gold nanowire at a precise position under normal conditions. The fabricated gold nanowire demonstrated excellent biosensing of IgA with an extremely low limit of detection (1 aM).
