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Erratum.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2022
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OPTN/SRTR 2020 Annual Data Report: Living Donor Collective

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2022
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OPTN/SRTR 2020 Annual Data Report: Introduction.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2022
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OPTN/SRTR 2020 Annual Data Report: VCA.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2022
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OPTN/SRTR 2020 Annual Data Report: Liver.

A J Kwong1, N H Ebel2, W R Kim1,3

  • 1Division of Gastroenterology and Hepatology, Stanford University, Palo Alto, CA.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|March 10, 2022
PubMed
Summary
This summary is machine-generated.

Despite the COVID-19 pandemic, 2020 saw a record number of liver transplants in the US, with improved survival metrics. Waitlists decreased, and new policies aimed to improve pediatric liver allocation.

Keywords:
Liver transplantallocationdistributionwaiting list

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Area of Science:

  • Transplantation Medicine
  • Hepatology
  • Public Health

Background:

  • The COVID-19 pandemic significantly impacted organ transplant programs globally.
  • Liver transplantation is a critical treatment for end-stage liver disease.
  • Previous years showed consistent growth in living donor liver transplantation.

Purpose of the Study:

  • To analyze the impact of the COVID-19 pandemic on liver transplant activity and outcomes in the US.
  • To evaluate the effects of new liver allocation policies implemented in 2020.
  • To identify trends in liver transplant indications and recipient demographics.

Main Methods:

  • Analysis of national liver transplant data from 142 US centers.
  • Review of pretransplant, graft, and patient survival metrics.
  • Assessment of waitlist dynamics and demographic trends.
  • Evaluation of policy changes including acuity circles and pediatric liver allocation.

Main Results:

  • A record 8906 liver transplants were performed, with improved survival rates despite the pandemic.
  • Living donation decreased, while overall waitlists for adult and pediatric recipients shrank.
  • New acuity circle policy and direct pediatric liver allocation showed mixed results, improving pediatric pretransplant mortality but not increasing absolute numbers.
  • Alcohol-associated liver disease became the leading indication for adult liver transplants.
  • Hepatocellular carcinoma transplant rates equalized with non-cancer cases post-policy changes.
  • Women continued to face higher pretransplant mortality and lower transplant rates.

Conclusions:

  • Liver transplant programs demonstrated resilience during the COVID-19 pandemic, achieving record volumes and improved outcomes.
  • Policy changes have begun to reshape liver allocation, with notable impacts on pediatric recipients and specific disease indications.
  • Persistent disparities in outcomes for women require further attention and intervention.