Related Experiment Video
Updated: Sep 30, 2025

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
Published on: September 11, 2015
Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration
Manuela González-Sánchez1, Pedro Rivero-Antúnez1,2, Rafael Cano-Crespo1
1Departamento Física de la Materia Condensada, Universidad de Sevilla, 41012 Sevilla, Spain.
Abstract:
In this work, a procedure for fabricating porous alumina with the use of a carbon sacrificial template has been tested in order to optimize the fabrication of porous structures mimicking the porosity and mechanical properties of the human cortical bone. Two different sources of sacrificial carbon were used and compared, and different sintering and calcination routes were considered. The porosity of the alumina structures studied by Hg porosimetry revealed that the amount of porosity and the size and shape of the pores are still below the required values, although some acicular pores were clearly observed by SEM. Moreover, measured mechanical properties (Young's modulus) remained below that of the bone, suggesting the need for further consolidation treatments. In summary, these encouraging results drive the optimization of future fabrication routes.

