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Cutaneous insulin reaction resembling acanthosis nigricans
Archives of Dermatology
|September 1, 1986
Summary
Repeated insulin injections can cause rare skin changes, leading to hyperkeratotic, verrucous plaques. This condition may be an unusual side effect of insulin
Area of Science:
- Dermatology
- Endocrinology
Background:
- Diabetes mellitus management requires regular insulin administration.
- Subcutaneous injection sites are prone to localized reactions.
Observation:
- A patient presented with hyperkeratotic, verrucous plaques.
- Lesions were exclusively located at sites of repeated insulin injections.
Findings:
- This case represents a rare cutaneous manifestation potentially linked to insulin therapy.
- Only one prior similar case has been documented in medical literature.
Implications:
- The findings suggest a possible unusual trophic effect of insulin on skin.
- Further investigation is warranted to understand the pathophysiology of insulin-induced skin lesions.
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