Related Experiment Video
Updated: Sep 30, 2025
10:05
In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays
Published on: September 20, 2021
2.5K
Construction and Sensing Amplification of Raspberry-Shaped MOF@MOF
Ming-Xue Wu1, Chunlei Wei1,2, Xing-Huo Wang1
1School of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, Shandong, P. R. China.
Inorganic Chemistry
|March 10, 2022
Summary
We developed raspberry-shaped metal-organic frameworks@metal-organic frameworks (MOFs@MOFs) for enhanced fluorescence sensing. These novel MOFs@MOFs show improved selectivity and sensitivity for detecting Hg2+ ions.
Area of Science:
- Materials Science
- Nanotechnology
- Chemical Sensing
Background:
- Metal-organic frameworks (MOFs) offer tunable structures for specific functions.
- Multilayer MOFs@MOFs present advantages over single MOFs but require synthesis and fluorescence property improvements.
Purpose of the Study:
- To construct a fluorescent raspberry-shaped MOF@MOF with enhanced sensing capabilities.
- To investigate the synthesis and fluorescence properties of the novel MOF@MOF structure.
Main Methods:
- Optimized seed-mediated synthesis of UiO-66-NH2 core and UiO-67-bpy shell.
- Characterization of raspberry-shaped UiO-66@67-bpy.
- Evaluation of sensing selectivity and performance for Hg2+ ions.
- Density Functional Theory (DFT) calculations for mechanism elucidation.
Main Results:
- Successfully synthesized raspberry-shaped UiO-66@67-bpy MOF@MOF.
- Demonstrated stable fluorescence and high selectivity for Hg2+ detection.
- Achieved amplified sensing performance compared to individual MOFs and mixed counterparts.
- DFT calculations indicated enhanced charge transfer due to outer shell enrichment.
Conclusions:
- The synergistic effect in MOFs@MOFs enhances fluorescence sensing performance.
- Raspberry-shaped UiO-66@67-bpy shows great potential for Hg2+ ion detection.
- This work unlocks possibilities for advanced sensors and other MOF-based applications.
Related Concept Videos
01:17MOSFET Amplifiers
229
The MOSFET, when operating in its active region, functions as a voltage-controlled current source. In this region, the gate-to-source voltage controls the drain current. This principle underlies the operation of the transconductance MOSFET amplifier. The output current is directed through a load resistor to convert this amplifier into a voltage amplifier. The output voltage is then obtained by subtracting the voltage drop across the load resistance from the supply voltage. This process results...
229
01:22Amplifying Signals via Enzymatic Cascade
11.3K
When a ligand binds to a cell-surface receptor, the receptor's intracellular domain changes shape, which may either activate its enzyme function or allow its binding to other molecules. The initial signal is amplified by most signal transduction pathways. This means that a single ligand molecule can activate multiple molecules of a downstream target. Proteins that relay a signal are most commonly phosphorylated at one or more sites, activating or inactivating the protein. Kinases catalyze...
11.3K
01:23Small-Signal Analysis of MOSFET Amplifiers
765
In small-signal analysis, a MOSFET transistor amplifier acts as a linear amplifier when operating in its saturation region. The gate-to-source voltage (VGS) of the MOSFET is the sum of the DC biasing voltage and the small time-varying input signal. This combination sets up the operating point and modulates the drain current (ID) that flows from the drain to the source. When a small AC signal is superimposed on the DC bias voltage at the gate, the instantaneous drain current comprises three...
765
01:20Design Example: Capacitance Multiplier Circuit
1.0K
In integrated circuit technology, a capacitance multiplier is often utilized to produce a larger capacitance value when a small physical capacitance falls short. This is achieved by a circuit that multiplies capacitance values by a factor of up to 1000, such that a 10-pF capacitor can replicate the performance of a 100-nF capacitor.
The circuit illustrated in Figure 1 below incorporates two op-amps, with the first operating as a voltage follower and the second acting as an inverting amplifier.
The circuit illustrated in Figure 1 below incorporates two op-amps, with the first operating as a voltage follower and the second acting as an inverting amplifier.
1.0K
01:15Amplifying Signals via Second Messengers
7.3K
Many receptor binding ligands are hydrophilic; they do not cross the cell membrane but bind to cell-surface receptors. Thus, their message must be relayed by second messengers present in the cell cytoplasm. There are several second messenger pathways, each with its own way of relaying information. For example, the G protein-coupled receptors can activate both phosphoinositol and cyclic AMP (cAMP) second messenger pathways. The phosphoinositol pathway is active when the receptor induces...
7.3K
01:16Cascaded Op Amps
771
Operational amplifiers (op-amps) are versatile electronic components that can be interconnected in a cascade - one after another in a linear sequence. This cascading is possible due to their infinite input resistance and zero output resistance, allowing them to maintain their input-output relationships even when connected in series.
In a cascaded system, each op-amp is referred to as a stage. The output of one stage drives the input of the subsequent stage. As the input signal passes through...
In a cascaded system, each op-amp is referred to as a stage. The output of one stage drives the input of the subsequent stage. As the input signal passes through...
771