Related Experiment Video
Updated: Jul 28, 2026
10:57
Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Anthelmintics and drug resistance
The Veterinary Clinics of North America. Equine Practice
|August 1, 1986
Summary
This review covers equine anthelmintics and parasite resistance, offering strategies to combat nematode infections and prevent future resistance. Effective treatment and management are key to controlling these equine parasites.
Area of Science:
- Veterinary Parasitology
- Equine Health
- Antimicrobial Resistance
Background:
- Nematode parasite infections are a significant health concern in horses.
- Anthelmintic resistance in equine nematodes is an increasing global problem.
- Effective parasite control is crucial for equine welfare and performance.
Purpose of the Study:
- To review current knowledge on equine anthelmintics.
- To discuss the issue of anthelmintic resistance in equine nematode parasites.
- To provide recommendations for effective treatment and future resistance management.
Main Methods:
- Literature review of scientific publications on equine anthelmintics.
- Analysis of data on anthelmintic resistance patterns.
- Synthesis of information to formulate treatment and management strategies.
Main Results:
- The review details various classes of equine anthelmintics.
- Evidence of widespread resistance to commonly used anthelmintics is presented.
- Specific nematode species exhibit varying resistance profiles.
Conclusions:
- Integrated parasite management strategies are essential for sustainable control.
- Responsible anthelmintic use is critical to slow the progression of resistance.
- Future research should focus on novel control methods and resistance monitoring.
More Related Videos
Related Concept Videos
02:56Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
01:17Drugs for Treatment of Diarrhea-Predominant IBS
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
01:30Development of Antibiotic Resistance
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
01:29Malaria
Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
01:15Anthelminthic Agents
Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
01:21Antiprotozoal Agents
Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...