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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
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American Head and Neck Society Endocrine Surgery Section and International Thyroid Oncology Group consensus statement

David C Shonka1, Alan Ho2, Ashish V Chintakuntlawar3

  • 1Department of Otolaryngology - Head and Neck Surgery, University of Virginia, Charlottesville, Virginia, USA.

Head & Neck
|March 11, 2022
PubMed
Abstract

Insights

This evidence-based statement defines advanced thyroid cancer and its targeted systemic treatments. It provides consensus statements on molecular evaluation and therapies for better patient outcomes.

Area of Science:

  • Oncology
  • Molecular Biology
  • Evidence-Based Medicine

Background:

  • The molecular landscape of advanced thyroid cancer is driving the development of novel systemic treatments.
  • A multidisciplinary, evidence-based approach is crucial for defining advanced thyroid cancer and its management.

Purpose of the Study:

  • To establish a consensus definition for advanced thyroid cancer.
  • To provide evidence-based statements on the molecular evaluation and targeted systemic treatment of advanced thyroid cancer.

Main Methods:

  • An expert panel was convened to review the literature on advanced thyroid cancer.
  • Best practice statements were developed using a modified Delphi method to ensure consensus.

Main Results:

  • A review of thyroid cancer oncogenesis at the molecular level is presented.
  • Characteristics of advanced thyroid cancer are defined.
  • Twenty consensus statements cover multidisciplinary management, molecular testing, and targeted systemic therapies.

Conclusions:

  • A consensus definition and management guidelines for advanced thyroid cancer are needed due to expanding targeted therapies.
  • Molecular testing and targeted systemic treatments are essential components of managing advanced thyroid cancer.
Keywords:
advanced thyroid cancerconsensus statementmolecular testingsystemic therapytargeted treatment

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