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Updated: Sep 30, 2025
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Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
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Probiotics Properties: A Focus on Pregnancy Outcomes
Karim Seif El Dahan1, Joseph Bejjani1, Ali A Nasrallah1
1Faculty of Medicine, American University of Beirut, Lebanon.
Summary
Probiotic supplementation during pregnancy, particularly with lactobacilli and Bifidobacterium, shows potential benefits for maternal and infant health. Further research is needed to confirm these promising findings for expectant mothers.
Area of Science:
- Microbiology
- Obstetrics
- Immunology
Background:
- A healthy microbiome is crucial for overall health, including reproductive wellness.
- The role of probiotics in pregnancy remains underexplored despite their known benefits in other systems.
Purpose of the Study:
- To review the potential benefits and risks of probiotic use during pregnancy.
- To synthesize current literature on probiotics and pregnancy outcomes.
Main Methods:
- A comprehensive literature search was conducted over the past decade.
- Databases used included PubMed, Medline, Google Scholar, Ovid, Scopus, and Science Direct.
- Data from 40 selected articles were analyzed.
Main Results:
- Prenatal and postnatal probiotic supplementation may offer protective effects.
- Probiotics may reduce the risk of gestational diabetes by improving insulin resistance.
- Potential benefits include reduced anxiety/depression, improved vaginal flora, and decreased infant eczema.
- Probiotics may prevent allergic reactions by modulating immune responses during gestation.
Conclusions:
- Leveraging cervicovaginal microbiota through probiotics may enhance pregnancy outcomes.
- Careful selection, dosing, and monitoring of probiotics are essential.
- More extensive randomized clinical trials are required to establish definitive clinical guidelines.
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