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Published on: March 15, 2024
Dietary Patterns Following an Episode of Acute Pancreatitis: A Post Hoc Analysis From the PAPPEI Multicenter,
Kristen M Roberts1,2, Sasathorn Thongkhao-On1, Stacey Culp3
1The School of Health and Rehabilitation Sciences.
Background:
Acute pancreatitis (AP) is a common disease resulting in local and systemic inflammation. It is now recognized that long-term complications can develop after an AP episode, including persistent GI symptoms, exocrine pancreatic dysfunction (EPD), and recurrence of AP. Although nutrition plays a key role in recovery, the impact of diet patterns on gastrointestinal (GI) symptoms and recurrent AP remains unclear.
Methods:
A secondary analysis of participants from the multicenter, post-acute pancreatic exocrine insufficiency (PAPPEI) study who completed a standardized dietary questionnaire was performed to assess dietary patterns after AP. A dietary pattern score was developed to compare dietary changes over time, where a higher score reflects a more favorable dietary pattern.
Results:
Significant changes in dietary pattern scores were observed over time with average scores peaking at 3 months (10.3 ± 3.0) then declining at one year (9.2 ± 3.0) ( P =0.024). Lower baseline dietary pattern scores were linked to recurrent AP ( P = 0.035), >10% weight loss ( P =0.016), and persistent GI symptoms ( P =0.030) at 12 months.
Conclusions:
Dietary patterns may contribute to the development of GI symptoms, weight loss, and recurrent AP. Further research validating our observations and investigations into dietary interventions to reduce GI symptoms and disease recurrence is warranted.
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Assessment:
01:25Acute Pancreatitis I: Introduction
01:27Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
01:25Chronic Pancreatitis I: Introduction
01:24Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...