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Persistent cough and asthma-like symptoms post COVID-19 hospitalization in children

Hossein Esmaeilzadeh1,2, Anahita Sanaei Dashti3, Negar Mortazavi4

  • 1Allergy Research Center, Shiraz University of Medical Sciences, P. O. Box 719335899, Shiraz, Iran. esmailzadeh_ho@yahoo.com.

BMC Infectious Diseases
|March 13, 2022
PubMed

Insights

COVID-19 hospitalization increases the risk of developing persistent cough and asthma-like symptoms in children. A history of asthma or allergic rhinitis significantly elevates this risk.

Area of Science:

  • Pediatric Respiratory Medicine
  • Infectious Diseases
  • Epidemiology

Background:

  • Respiratory viruses are primary asthma triggers.
  • Coronaviruses can cause prolonged cough and asthma following respiratory infections.

Purpose of the Study:

  • To determine the risk of persistent cough and asthma-like symptoms in children hospitalized with COVID-19.
  • To identify risk factors associated with developing asthma-like symptoms post-COVID-19 hospitalization.

Main Methods:

  • Prospective study of 69 pediatric patients hospitalized with COVID-19.
  • Follow-up evaluations for cough and asthma symptoms at 1, 2, and 6 months post-discharge.
  • Comparison of asthma-like and non-asthma groups regarding medical history and risk factors.

Main Results:

  • 41.5% of hospitalized children developed asthma-like symptoms.
  • Asthma-like group showed higher rates of family history of asthma (63.0%), prior asthma (33.3%), and allergic rhinitis (85.2%).
  • COVID-19 presentations were more severe in the asthma-like group.

Conclusions:

  • Hospitalized COVID-19 children have a significant risk of developing asthma-like symptoms.
  • Family history of asthma, prior asthma, and allergic rhinitis are key risk factors.
  • Pre-existing asthma conditions worsen COVID-19 severity in children.
Abstract

Keywords:
AsthmaCOVID-19ChildHospitalization

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