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Related Concept Videos

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Pulmonary Function Tests01:25

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Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
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Related Experiment Video

Updated: Sep 30, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
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Dynamic Changes in Lung Function and Imaging in Patients with COVID-19.

Lingyan Ye1, Bingyu Hu2, Shuangxiang Lin2

  • 1Department of Respiratory Medicine, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China.

The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale
|March 14, 2022
PubMed
Summary

COVID-19 survivors show significant lung imaging improvement three months post-discharge, with most abnormalities resolving. However, some patients experience persistent mild to moderate pulmonary dysfunction, including restrictive and small airway issues.

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Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Radiology

Background:

  • COVID-19 (Coronavirus Disease 2019) can lead to significant respiratory complications.
  • Understanding long-term lung function and imaging changes post-infection is crucial for patient recovery.
  • Assessing the correlation between imaging findings and pulmonary function provides insights into disease sequelae.

Purpose of the Study:

  • To evaluate lung function and chest imaging recovery in COVID-19 patients three months after clinical cure.
  • To determine the correlation between lung function and chest imaging findings at three months post-discharge.

Main Methods:

  • Retrospective analysis of 80 COVID-19 patients discharged from a medical center.
  • Lung function tests and CT scans performed at discharge and three months later.
  • Correlation analysis of dynamic changes in imaging and pulmonary function.

Main Results:

  • At three months post-discharge, 97.5% of patients showed improved chest imaging, with only 12.5% exhibiting residual abnormalities.
  • Pulmonary dysfunction decreased significantly, but 22.5% had restrictive, 35% small airway, and 40% diffuse dysfunction.
  • More severe initial chest imaging findings correlated with greater residual lung function impairment.

Conclusions:

  • COVID-19 patients demonstrate substantial recovery in chest imaging within three months, with minimal residual fibrosis.
  • Mild to moderate pulmonary dysfunction, particularly restrictive and small airway issues, can persist post-recovery.
  • The study highlights the importance of follow-up assessments for persistent respiratory sequelae.