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Post coronavirus disease mucormycosis involving the mandible: A case report with brief note on literature
Lokesh Bhanumurthy1, P Sai Krishna1, Prasanna Sekhar1
1Department of Oral Pathology, Tagore Dental College and Hospital, Chennai, Tamil Nadu, India.
Abstract:
Mucormycosis also termed as phycomycosis or zygomycosis is less commonly seen in oral cavity. However, it is an invasive, life-threatening and aggressive fungal infection. It mostly targets individuals with altered immunological system and diabetes. In this recent pandemic situation, the individuals affected with coronavirus disease 2019 (COVID-19) are also affected with this fungal infection which commonly involves the maxilla. In this case report, we present a case of a 45-year-old female affected with mucormycosis in post-COVID scenario involving mandible which is quite rare situation. The case report covers clinical findings, radiographic investigations and histopathological details with brief on literature review. Since mucormycosis is aggressive fungal infection, it should be handled with multimodal approach to reduce the systemic damage of an individual, morbidity and mortality.
Insights
Mucormycosis, a rare aggressive fungal infection, can affect the mandible in post-COVID-19 patients, posing a significant threat. Early diagnosis and multimodal treatment are crucial for managing this life-threatening condition.
Area of Science:
- Oral Medicine
- Infectious Diseases
- Mycology
Background:
- Mucormycosis, a severe fungal infection, typically affects immunocompromised individuals, including those with diabetes.
- While commonly affecting the maxilla, oral mucormycosis is less frequent.
- The recent increase in mucormycosis cases associated with coronavirus disease 2019 (COVID-19) highlights its opportunistic nature.
Observation:
- This case report details a rare instance of mucormycosis involving the mandible in a 45-year-old female patient during the post-COVID-19 period.
- Clinical, radiographic, and histopathological findings were documented.
- The presentation in the mandible is an unusual deviation from typical oral mucormycosis patterns.
Findings:
- The patient presented with a rare mandibular manifestation of mucormycosis.
- Diagnostic investigations confirmed the fungal infection.
- The literature review provided context for this unusual presentation.
Implications:
- This case underscores the importance of considering mucormycosis in immunocompromised patients, especially those with a history of COVID-19, even with atypical presentations.
- Aggressive fungal infections necessitate prompt diagnosis and a comprehensive, multimodal treatment strategy.
- Effective management is vital to minimize systemic damage, reduce morbidity, and improve patient outcomes.
