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Renal Salt-Wasting Syndrome Induced by Neoadjuvant Chemotherapy Containing Cisplatin - A Case Report
N Jinsi1, A Vimala1, Sreeja S Nair1
1Department of Nephrology, Cosmopolitan Hospital, Trivandrum, Kerala, India.
Chemotherapy-induced hyponatremia can stem from renal salt-wasting syndrome (RSWS) or SIADH, requiring different treatments. This case highlights a rare instance of cisplatin causing RSWS with additional renal abnormalities.
Area of Science:
- Oncology
- Nephrology
- Internal Medicine
Background:
- Hyponatremia is a frequent complication in cancer patients, often linked to chemotherapy.
- Chemotherapy-induced hyponatremia typically results from renal salt-wasting syndrome (RSWS) or syndrome of inappropriate antidiuretic hormone secretion (SIADH).
- Distinguishing between RSWS and SIADH is crucial for effective treatment, as management strategies differ significantly.
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