Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Controlling nanoparticle targeting: from physicochemical design to molecular recognition.

Nanomedicine (London, England)·2026
Same author

Gold decorated bismuth sulfide nanorods for enhanced computed tomography imaging with in vitro and in vivo validation.

Discover nano·2026
Same author

Programming Degradation and Drug Release Through Micropatterning of PLGA Films.

ACS applied materials & interfaces·2026
Same author

Alginate-based mucoadhesive nanofibrous system embedding resveratrol-loaded vesicles as a therapeutic platform for nasal disorders.

International journal of biological macromolecules·2026
Same author

Anticancer LNA Oligonucleotides Detection through a Simple Paper-Based Platform.

ACS measurement science au·2026
Same author

Enhancing Tumor Perfusion and Nanomedicine Delivery via Endogenous Nitric Oxide Release by Methyl Palmitate Nanoparticles.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Sep 30, 2025

Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation
10:16

Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation

Published on: October 12, 2018

8.1K

Shape-specific microfabricated particles for biomedical applications: a review.

Thomas L Moore1, Alexander B Cook2, Elena Bellotti2

  • 1Laboratory of Nanotechnology for Precision Medicine, Istituto Italiano Di Tecnologia, Via Morego, 30, 16163, Genoa, Italy. thomas.moore@iit.it.

Drug Delivery and Translational Research
|March 14, 2022
PubMed
Summary

This review explores microplates and discoidal polymeric particles for advanced drug delivery. These micro-scale systems offer tunable properties for treating various diseases, enhancing pharmaceutical applications.

More Related Videos

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
09:54

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics

Published on: September 10, 2018

7.6K
One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes
08:31

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Published on: September 13, 2018

10.0K

Related Experiment Videos

Last Updated: Sep 30, 2025

Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation
10:16

Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation

Published on: October 12, 2018

8.1K
Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
09:54

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics

Published on: September 10, 2018

7.6K
One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes
08:31

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Published on: September 13, 2018

10.0K

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Pharmaceutical Sciences

Background:

  • Controlled release systems have evolved significantly, from sutures to nano-formulations.
  • Particle drug delivery systems in the micron size range have been utilized since the 1980s.
  • Advances in micro/nanofabrication allow precise control over particle characteristics.

Purpose of the Study:

  • To review the utility of microplates and discoidal polymeric particles in pharmaceutical applications.
  • To highlight design and fabrication strategies for these micro-scale drug delivery systems.
  • To discuss their potential applications in treating various pathologies.

Main Methods:

  • Review of scientific literature on microplates and discoidal polymeric particles.
  • Analysis of micro/nanofabrication techniques for particle design.
  • Discussion of how particle properties (size, shape, stiffness, materials) influence functionality.

Main Results:

  • Microplates are cuboid polymeric local depot devices at the micrometer scale.
  • Discoidal polymeric nanoconstructs are disk-shaped particles with micrometer diameters and nanometer thickness.
  • These particles can be engineered for targeted delivery in conditions like cancer and inflammatory diseases.

Conclusions:

  • Microplates and discoidal polymeric particles represent versatile platforms for drug delivery.
  • Their tunable physico-chemical properties enable tailored therapeutic applications.
  • Emerging trends indicate significant potential for these micro-scale systems in future formulations.