Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

128
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
128
Peritoneal Dialysis I: Introduction and Procedure01:30

Peritoneal Dialysis I: Introduction and Procedure

368
Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
368
Peritoneal Dialysis III: Nursing Management01:25

Peritoneal Dialysis III: Nursing Management

181
Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
181
Dialysis01:27

Dialysis

530
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
530
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

62
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
62
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

364
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
364

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preserving Peritoneal Membrane Performance.

Clinical journal of the American Society of Nephrology : CJASN·2026
Same author

VExUS Point-of-Care Ultrasound Tool to Detect Changes in Volume Status: A Prospective Observational Study.

JACC. Advances·2026
Same author

Core Interventions for the Prevention of Peritoneal Dialysis-Related Infections.

Clinical journal of the American Society of Nephrology : CJASN·2025
Same author

Incremental start and clinical outcomes in peritoneal dialysis: International results from PDOPPS.

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis·2025
Same author

Response to "Icodextrin lowers serum sodium in dose-dependent fashion: A case report" : Keep calm and continue Icodextrin.

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis·2025
Same author

International Society for Peritoneal Dialysis Journal Club: Bridging the Gap between Trainee Education and Home Dialysis Demand.

Clinical journal of the American Society of Nephrology : CJASN·2025

Related Experiment Video

Updated: Sep 30, 2025

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

2.7K

Peritoneal dialysis adequacy: a paradigm shift.

Chang Huei Chen1, Isaac Teitelbaum1

  • 1Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Kidney Research and Clinical Practice
|March 14, 2022
PubMed
Summary
This summary is machine-generated.

Peritoneal dialysis (PD) adequacy should move beyond Kt/Vurea. New guidelines emphasize a holistic patient assessment for high-quality PD care, including quality of life and symptom burden.

Keywords:
AdequacyMetabolic acidosisPeritoneal dialysisResidual kidney functionVolume overload

More Related Videos

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

15.5K
Laparoscopic-Assisted Seldinger Technique for Peritoneal Dialysis Catheter Insertion
06:23

Laparoscopic-Assisted Seldinger Technique for Peritoneal Dialysis Catheter Insertion

Published on: May 23, 2025

680

Related Experiment Videos

Last Updated: Sep 30, 2025

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

2.7K
Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

15.5K
Laparoscopic-Assisted Seldinger Technique for Peritoneal Dialysis Catheter Insertion
06:23

Laparoscopic-Assisted Seldinger Technique for Peritoneal Dialysis Catheter Insertion

Published on: May 23, 2025

680

Area of Science:

  • Nephrology
  • Renal Medicine
  • Dialysis Therapy

Background:

  • Historically, Kt/Vurea has been the primary metric for assessing peritoneal dialysis (PD) adequacy.
  • Evidence supporting Kt/Vurea as a sole indicator of uremic symptom control or nutritional status in PD patients is lacking.
  • Accurate determination of total body water (TBW), essential for Vurea calculation, is challenging.

Purpose of the Study:

  • To highlight the limitations of relying solely on Kt/Vurea for PD adequacy assessment.
  • To introduce the paradigm shift towards comprehensive patient evaluation in PD care.
  • To advocate for the adoption of multiple measures for high-quality PD.

Main Methods:

  • Review of current International Society for Peritoneal Dialysis (ISPD) practice recommendations.
  • Emphasis on incorporating multiple assessment parameters beyond Kt/Vurea.
  • Focus on patient-centered care, including shared decision-making and quality of life.

Main Results:

  • Kt/Vurea is not a reliable surrogate for uremic symptom control or nutritional status.
  • ISPD guidelines now recommend a multifactorial approach to PD assessment.
  • Comprehensive assessment includes quality of life, symptom burden, residual kidney function, volume status, and biochemical markers.

Conclusions:

  • A paradigm shift is occurring in PD care, moving from sole reliance on Kt/Vurea to a holistic patient assessment.
  • High-quality PD care necessitates evaluating the patient comprehensively, not just solute clearance.
  • Tailoring PD prescriptions based on individual patient priorities and goals is crucial for optimal outcomes.