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Related Experiment Video

Updated: Sep 30, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Bowen's Disease.

Vijayasankar Palaniappan1, Kaliaperumal Karthikeyan1

  • 1Department of Dermatology, Venereology and Leprosy, Sri ManakulaVinayagar Medical College and Hospital, Puducherry, India.

Indian Dermatology Online Journal
|March 15, 2022
PubMed
Summary
This summary is machine-generated.

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Bowen's disease (BD), an early skin cancer, has varied causes and appearance. Diagnosis relies on histopathology, with treatments tailored to individual patient factors.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Bowen's disease (BD) is a non-invasive squamous cell carcinoma confined to the epidermis.
  • It has a multifactorial etiology, with a higher incidence observed in Caucasian populations.
  • BD commonly affects sun-exposed skin but can occur elsewhere, typically presenting as solitary lesions.

Purpose of the Study:

  • To provide a comprehensive overview of Bowen's disease.
  • To discuss diagnostic modalities and treatment strategies for BD.
  • To highlight the multidisciplinary approach required for managing BD.

Main Methods:

  • Review of existing literature on Bowen's disease.
  • Discussion of histopathological findings as the gold standard for diagnosis.
  • Exploration of adjuvant diagnostic tools like immunohistochemistry, dermoscopy, and reflectance confocal microscopy.
Keywords:
Bowen's diseaseerythroplasia of Queyratsquamous cell carcinoma

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Main Results:

  • The morphology of BD varies with lesion age, site, and keratinization.
  • BD is a precursor to invasive squamous cell carcinoma.
  • Multiple treatment options exist, including topical chemotherapy, surgery, light-based therapies, and destructive methods.

Conclusions:

  • Accurate diagnosis of BD is crucial and primarily achieved through histopathology.
  • Treatment selection for BD is individualized, considering lesion characteristics and patient factors.
  • Effective management of BD necessitates collaboration among dermatologists, oncosurgeons, and plastic surgeons.