Cutaneous larva migrans.
Vijayasankar Palaniappan1, Hima Gopinath2, Kaliaperumal Karthikeyan1
1Department of Dermatology, Venereology and Leprosy, Sri Manakula Vinayagar Medical College and Hospital, Pondicherry, India.
Clinical and Experimental Dermatology
|August 12, 2025
Summary
Cutaneous larva migrans, a parasitic skin infection, is caused by hookworm larvae entering the skin. It presents as itchy tracks and is increasingly found in non-endemic areas due to climate change and travel.
Area of Science:
- Parasitology
- Dermatology
- Epidemiology
Background:
- Cutaneous larva migrans (CLM) is a parasitic skin disease caused by nematode larvae, primarily from Ancylostoma species.
- It is endemic in tropical/subtropical areas, characterized by pruritic, serpiginous tracks from larval migration in the epidermis.
- CLM significantly affects quality of life, particularly in resource-limited settings.
Purpose of the Study:
- To summarize the etiology, clinical presentation, diagnosis, treatment, and prevention of CLM.
- To highlight the expanding geographic distribution of CLM due to global environmental and social changes.
- To emphasize the importance of recognizing CLM variants and its increasing prevalence in non-endemic regions.
Main Methods:
- Literature review of CLM, focusing on parasitic causes, clinical manifestations, and epidemiological trends.
- Analysis of diagnostic approaches, including clinical evaluation and treatment options.
- Synthesis of information on preventive strategies and public health implications.
Main Results:
- CLM is caused by hookworm larvae (e.g., Ancylostoma braziliense, A. caninum) entering the skin via contaminated soil/sand.
- Clinical presentation includes intensely itchy, winding red tracks; variants like follicular and bullous forms exist.
- Diagnosis is typically clinical; oral anti-helminthics (albendazole, ivermectin) are effective treatments.
Conclusions:
- CLM is a growing public health concern with expanding geographic range due to climate change, travel, and urbanization.
- Timely diagnosis and management are crucial, especially in non-endemic regions where awareness may be limited.
- Prevention through sanitation, pet deworming, and protective footwear is vital in endemic and newly affected areas.
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