Related Experiment Video
Updated: Sep 30, 2025

Ischemic Tissue Injury in the Dorsal Skinfold Chamber of the Mouse: A Skin Flap Model to Investigate Acute Persistent Ischemia
Published on: November 17, 2014
Facial Vascular Events and Tissue Ischemia: A Guide to Understanding and Optimizing Wound Care
Astra Farmer1,2,3,4,5, Gillian Murray1,2,3,4,5, Brittony Croasdell1,2,3,4,5
1Ms. Farmer is with Devon and Cornwall Aesthetics Academy in Exmouth, England.
Abstract:
The Complications in Medical Aesthetics Collaborative (CMAC) is a nonprofit organization established to promote best patient outcomes through educating clinicians in the prevention, diagnosis, and management of complications that can arise following nonsurgical cosmetic procedures. The organization is a global community sharing information, learning, experience, and data to promote best practices. This article explores how dermal filler vascular events can cause tissue ischaemia leading to a facial wound. Ideally, vascular events will be diagnosed early and amenable to reversal with hyaluronidase if caused by a cross-linked hyaluronic acid. If there is significant and extensive hypoxia to the area, there is delayed diagnosis, or the injected product cannot be reversed, the management should center around optimizing wound care. Both simple and complex wounds will benefit from good care. Patients seek aesthetic treatments to improve how they look and can be vulnerable to poor outcomes. Wounds, if not treated appropriately, can result in permanent scarring or other sequalae, such as post-inflammatory hyperpigmentation. There are many publications addressing vascular events in aesthetic practice, but providing optimal care for facial wounds is not addressed.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Vascular Spasm
Venous Thrombosis IV: Nursing Management
Peripheral Artery Disease IV: Nursing Management
Phases of Wound Repair
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Venous Thrombosis III: Interprofessional Care

