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An Unusual Case of Chronic Lymphocytic Leukaemia Involving the Cervix
Jack Hamer1, Maher Alazizi2, Farshad Tahmasebi2
1Obstetrics and Gynaecology, Walsall Manor Hospital, The Walsall Healthcare National Health Service Trust, Walsall, GBR.
Abstract:
Chronic lymphocytic leukaemia (CLL) is a malignant monoclonal expansion of B lymphocytes, with accumulation of abnormal lymphocytes in the blood, bone marrow, spleen, lymph nodes and liver. It is mainly a disease of the elderly population. Though extra-nodal involvement is common, cervical and vulvovaginal involvement by CLL is particularly uncommon. In this case report, we discuss the case of cervical involvement of CLL in an 84-year-old patient who presented to rapid-access gynaecological clinic following concerns of persistent postmenopausal bleeding. Previously the patient was known to haematology with a well-controlled diagnosis of CLL since 2007. The initial examination was significant for an enlarged, irregular cervix, whereby a punch biopsy was then obtained. Histological analysis revealed evidence of CLL within the cervix.
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