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Updated: Sep 30, 2025

Production of Monoclonal Antibodies Targeting Aminopeptidase N in the Porcine Intestinal Mucosal Epithelium
Published on: May 18, 2021
Engineering monoclonal antibodies for COVID-19 prophylaxis
Amin Izadpanah1, Jay Rappaport1
1Tulane National Primate Research Center, Department of Microbiology and Immunology, Tulane University School of Medicine, 18703 Three Rivers Road, Covington LA 70411, USA.
Abstract:
The therapeutic and prophylactic uses of monoclonal antibodies (mABs) against SARS-CoV-2 are limited by their short half-life and need for intravenous delivery. In this issue, Cobb et al.1 engineer a neutralizing mAB cocktail with extended half-life that can be delivered intramuscularly to provide prophylactic protection against infection in rhesus macaques.
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