Current commercial dPCR platforms: technology and market review.
Li Ling Tan1,2, Nitin Loganathan1, Sushama Agarwalla3
1Singapore Institute of Manufacturing Technology, Singapore, Singapore.
Critical Reviews in Biotechnology
|March 16, 2022
Summary
Digital polymerase chain reaction (dPCR) offers superior molecular diagnostics compared to qPCR. This review compares commercial dPCR instruments, their technologies, applications, and future trends.
Area of Science:
- Molecular Diagnostics
- Biotechnology
- Genomics
Background:
- Digital polymerase chain reaction (dPCR) presents advancements in molecular diagnostics.
- dPCR offers enhanced sensitivity, precision, and specificity over quantitative real-time PCR (qPCR).
Purpose of the Study:
- To review and compare commercial dPCR instruments from eight companies.
- To analyze technical aspects, usability, costs, and applications of available dPCR devices.
- To discuss emerging dPCR technologies and future market trends.
Main Methods:
- Comparative analysis of commercial dPCR instruments.
- Review of technical specifications, user-friendliness, and cost-effectiveness.
- Assessment of current applications and future technological developments in dPCR.
Main Results:
- Eight companies offer distinct dPCR instruments with varying features.
- Detailed comparison of technical aspects, usability, costs, and applications provided.
- Insights into up-and-coming dPCR technologies and their potential impact.
Conclusions:
- dPCR technology provides significant advantages for molecular diagnostics.
- A comprehensive understanding of current dPCR platforms is crucial for researchers and clinicians.
- Anticipation of future innovations will shape the dPCR landscape.
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