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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

483
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
483
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

217
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
217
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

493
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
493
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

258
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
258
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

347
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
347
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

923
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
923

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Related Experiment Video

Updated: Sep 30, 2025

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
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Pott's disease (tuberculous spondylitis).

Inês Almeida Pintor1, Flávio Pereira1, Susana Cavadas1

  • 1Department of Internal Medicine, Aveiro Hospital Center, Portugal.

International Journal of Mycobacteriology
|March 17, 2022
PubMed
Summary

Pott's disease, a vertebral tuberculosis, can present atypically, delaying diagnosis and treatment. Early detection through advanced imaging and molecular tests is crucial for managing spinal cord compression.

Keywords:
Antitubercular drugsMycobacterium tuberculosislatent tuberculosis infectionspinal cord compression

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Area of Science:

  • Infectious Diseases
  • Neurology
  • Radiology

Background:

  • Pott's disease, caused by Mycobacterium tuberculosis, often has an indolent course leading to delayed diagnosis.
  • Vertebral tuberculosis requires prompt identification to prevent severe neurological complications.

Observation:

  • A 79-year-old female presented with atypical symptoms including back pain, anorexia, and weight loss.
  • Initial CT revealed lytic lesions, while MRI showed T7-T8 spondylodiscitis with spinal cord compression.
  • Diagnostic workup included laboratory tests, imaging, and polymerase chain reaction (PCR) on T8 aspirate.

Findings:

  • Despite initial negative cultures, PCR confirmed Mycobacterium tuberculosis in the T8 aspirate.
  • Antitubercular treatment led to clinical improvement, but paraparesis developed, necessitating neurosurgery.
  • The case highlights diagnostic challenges due to rare, atypical presentations of vertebral tuberculosis.

Implications:

  • Emphasizes the importance of considering Pott's disease in elderly patients with vague symptoms and spinal lesions.
  • Highlights the utility of PCR in diagnosing tuberculosis when conventional methods fail.
  • Underscores the need for multidisciplinary approaches involving internal medicine, radiology, and neurosurgery for optimal patient outcomes.