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Updated: Sep 30, 2025

Natural Killer NK and CAR-NK Cell Expansion Method using Membrane Bound-IL-21-Modified B Cell Line
Published on: February 8, 2022
Facial Natural Killer/T-Cell Lymphoma: A Deadly Sinusitis Mimic
Rachel E Bridwell1, Steve C Gillis2, Gerrit W Davis1
1Emergency Medicine, Madigan Army Medical Center, Joint Base Lewis-McChord, USA.
Abstract:
Sinusitis and pre-septal cellulitis are common emergency department (ED) conditions, though rare and lethal mimics can present in a similar manner. We present a case of natural killer (NK)/T-cell lymphoma mimicking sinusitis and pre-septal cellulitis. Diagnosis of this condition may include imaging modalities such as CT and MRI, though definitive diagnosis requires tissue biopsy. Therapeutic interventions involve chemotherapy and radiation, with little role for surgical debridement. Complications in treatment can occur including hemophagocytic lymphohistiocytosis. Despite standard treatments, mortality remains high for cases of facial lymphoma.
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